Scientist
Groundbreaking Discoveries2013届毕业生利用人工智能和自动化加速发现和开发挽救生命的肽治疗严重疾病, including cancer.
Scientist
Groundbreaking Discoveries2013届毕业生利用人工智能和自动化加速发现和开发挽救生命的肽治疗严重疾病, including cancer.

WHEN HE WAS 10-YEARS-OLD, Dale Thomas had maps hanging in his bedroom. 令他着迷的是地图是如何根据当时已知的知识绘制的, and how later discoveries altered those maps. If he had a map predicting his own future, it would show a journey from his hometown of Hampden, Maine, to bridges of ships, 对人类生物学的深层化学轮廓的科学探索和多肽的研究.

Dale Thomas

Dale Thomas ’13
Cofounded Mytide Therapeutics

Thomas ’13 cofounded Mytide Therapeutics, 该公司利用人工智能和自动化技术缩短了生产多肽所需的时间, which have become valued in medical research and treatment. Mytide平台的承诺之一是,研究人员可以为特定的单个病人“订购”一种肽,作为他或她的癌症治疗的一部分. According to Thomas, 该公司正在努力使多肽在不久的将来成为一种低成本的个性化治疗.

肽是细胞和全身传递信号的基石. They have traditionally been expensive and time-consuming to produce, requiring six weeks to create by traditional methods in a laboratory. 托马斯和他的同事们设定了一个目标,要在近23小时内生产出多肽.

When humans develop cancer or other diseases, certain critical failures can happen inside of individual cells. 肽的大小适合进入细胞,并且可以携带其他物质,比如治疗药物. 设计和分子工程的进展使这些疗法成为治疗复杂疾病的实际解决方案. Indeed, 一些针对COVID-19的疫苗被设计成允许一个微小的脂肪容器携带一个信使RNA,以帮助刺激免疫反应.

“我一直在寻找机会,积极影响人们的生活. I believe whether you are moving a ship or you are creating medicines, they present a similar set of problems.”

在生物技术领域,多肽的市场价格估计为28美元.雅虎财经(Yahoo Finance)的一项分析显示,如果不包括胰岛素,美国2020年的糖尿病患者为40亿人. Biological building blocks, like peptides, 生物技术行业是否正在复苏,因为公司希望通过更个性化的方法更快地治愈越来越难的疾病.

UNCONVENTIONAL THINKER

As an only child, Thomas was raised in a family where education was valued, 他回忆说,他的抱负最终包括在研究生院学习科学和工程. He attended Hampden Academy where he enjoyed academics, 他认为缅因海事学院(MMA)是学习工程学的好地方.

At MMA, he learned to be a leader. 托马斯的一名工程学教授形容他“勤奋准备”, unconventional thinking, and sheer fortitude.托马斯以4年时间完成5年系统工程学位而闻名,并被授予2013届毕业生代表和舍尔最靠谱的网赌软件称号.

peptide building block

“我想进入航运业,或者在乔治亚太平洋公司的造纸厂工作, and then in my senior year, I applied to Stanford, Columbia, and Massachusetts Institute of Technology (MIT),” he recalled. He was accepted and landed at MIT, choosing a graduate program in manufacturing engineering, continuing on to earn a Ph.D. 在机械工程方面,他取得了完美的平均绩点.

For him, MIT would provide a fertile place for a wide range of sciences, engineering, and entrepreneurship.

“I was able to refine my unique systems level approach, 并真正看到了我的经验如何结合起来,解决了制造分子(如肽)数十年来的问题,,” he said. He called this a “serendipitous loop.”

他对领导能力的一些兴趣可能来自于他和祖父在布鲁克斯度过的初夏, Maine.

“我和他一起工作,看着他像一个老板一样思考……从这种灵感中,我确实想在某个时候创办自己的公司。. 基于这样的背景,我利用了在麻省理工学院学习创业的优势,”他说.

In hindsight, 当托马斯回顾他职业生涯的实际步骤时, he is satisfied with his choices.

“我一直在寻找机会,积极影响人们的生活. I believe whether you are moving a ship or you are creating medicines, they present a similar set of problems. 在我的职业生涯中,我很幸运能够充分探索我的求知欲,并致力于推动跨行业的影响.

MMA's ABS Building

多亏了ABS奖学金,Thomas才得以完成他在麻省理工学院的研究生学业. MMA’s ABS Center for Engineering, Science, 研究部提供最先进的教学和研究实验室, classrooms, study spaces, 在校园的中心会有更多的人来激励未来的工程师和科学家.

“A ship is a floating city. 那个城市有电,有动力,还有制冷系统. 缅因海事帮助我专注于复杂系统。”托马斯说.

Today, he lives and works in Boston. 他说,操纵一艘拥有复杂系统和专家团队的城市大小的船,与操纵一家制造复杂分子的公司没有什么区别.

当被问及是否有什么爱好时,托马斯笑着说他的公司就是他的爱好.

“I’m still working on a work-life balance formula.”

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